Sharing is caring!

Misoprostol is often called the “miscarriage pill,” as it helps women who’ve lost a pregnancy actually expel that pregnancy from their bodies. So yes, it’s as gross and horrifying as it sounds. It’s the generic form of a drug called Cytotec, used to induce miscarriage. In this article, Arden Cartrette discusses her terrifying misoprostol experience, the timeline of her misoprostol miscarriage, and why she wishes she’d read other misoprostol stories before taking it for an incomplete miscarriage.

Click here to subscribe

Arden’s Cytotec Story

When the doctor said the words “I’m sorry but it looks like there’s no heartbeat,” it confirmed our worst nightmare. A second miscarriage. I was in a state of shock. 

With our first miscarriage, I opted for a dilation & curettage (D&C) right away because the thought of going through a miscarriage at home was terrifying. Ultimately, my body had a plan all along, and I miscarried naturally, at-home, the night before the scheduled procedure. 

As the doctor was confirming our second loss, I kept thinking about how I really wanted it to be over as soon as it possibly could be. So I asked him to prescribe me the miscarriage pill and told him that I would induce the physical miscarriage at home. 

The “miscarriage pill” medication is called Misoprostol, which is the generic version of Cytotec. 

What Is Misoprostol?

Misoprostol is used to help the body complete a miscarriage.

“Misoprostol has been used off-label for many years as a safe and effective treatment for first-trimester incomplete miscarriage. Misoprostol binds to smooth muscle myometrium and causes uterine contractions.” 

American Academy of Family Physicians (AAFP)

This causes the body to let go of the pregnancy, which is helpful in the case of a missed miscarriage, when the body doesn’t recognize the loss and miscarry naturally.

(Editorial warning: If you see your medical chart, this might be labeled a “medical abortion.” This is standard medical terminology and has nothing to do with how wanted your loss was. Learn more about the medical term for miscarriage here.)

The AAFP definition of Misoprostol is “safe.” Still, if you read the drug information, you’ll see that misoprostol side effects can be VERY extreme.

Effects of misoprostol may include heavy bleeding and clotthing, to the point that you require medical attention. Call your doctor for advice about the amount of bleeding. It’s a great way to help with reducing the risks associated with misoprostol.

Plenty of people have good experiences using Cytotec for miscarriage, but there are also plenty of horror stories. Being educated about the drug will help you manage.

Personally, my misoprostol experience was horrific.

Is Misoprostol Safe for Miscarriage?

When you are told that your baby is no longer growing and that you should prepare for a miscarriage, you are normally given three options.

While no option is better than another, being educated about these decisions allows us to make the right decision for us.

To carry out a miscarriage, your options are:

  1. Waiting for your body to catch up and letting it happen “naturally”
  2. Taking a Misoprostol to induce the miscarriage
  3. Scheduling a D&C where you are put under general anesthesia while the tissue is removed from your body

At the time of my second miscarriage, I thought that I was making the right decision because taking Misoprostol would give me control, and I desperately needed some control.

(Editorial note: This thought process shows how different the experience of miscarriage is for everyone. When given the choice, Katy elected to have a D&C because she thought using misoprostol for incomplete miscarriage felt too uncontrolled.)

My journey felt out of control because things weren’t going as I planned they would.

But that’s just what a fertility journey is: unplanned chaos.

However, I wish I had known then what I know now about taking Misoprostol–side effects, stories, bad experiences, and all.

While it is deemed “safe” for inducing miscarriage by organizations like the American Academy of Family Physicians, that was not my Misoprostol experience.

My Misoprostol Experience

After I asked the doctor for misoprostol, often known as the miscarriage pill, he sent me on my way, and I planned to take the four tablets to induce the miscarriage the next day.

Saturday, February 9, 2019, at three o’clock in the afternoon.

I chose a specific time so I would hold myself to it.

It gave me the morning to say goodbye, do whatever I needed to do, and then I could have some control over when the worst would happen.

I set an alarm on my phone, went to the nearest store, and bought essential items like maxi pads, and adult diapers.

 Although I felt hurt and confused,I just wanted this to be over.

I was tired of constantly feeling like I was pregnant and miscarrying. 

For the past six months, that was all my life was, and after a year-and-a-half of infertility, I was fed up with things not working out the way that I thought that they would.

How Was I Supposed to Take this Miscarriage Pill?

When three o’clock came around, I held the four tablets in my hand and prepared to take them. 

They symbolized the physical end of my second pregnancy and still, I had nothing to show for it. 

How was I supposed to willingly take a medication that would evacuate a pregnancy from my body? 

How was this happening to us, again

It didn’t seem real. 

My husband, Kerry, sat next to me on our couch as I prepared to take the medication. He reminded me that this wasn’t my fault and that soon the physical part of this loss would be over. He reminded me that I wasn’t in this alone and that was reassuring, but as I took the tablets one by one, I couldn’t hold back my tears. 

Arden, the author of this article, in a selfie with her husband Kerry

Once again, I was afraid for my future. 

Could I handle another miscarriage? 

Would I ever have a healthy pregnancy?

The first step to finding out the answer to either of those questions was to take the medication, so that’s what I did.

My Misoprostol Miscarriage Timeline

 Roughly an hour after taking the misoprostol, the cramping started.

As a woman with semi-regular periods, I knew that first came cramping and then came bleeding. Another hour later, I noticed that the spotting had begun.

I excused myself to the bathroom so that I could labor and miscarry. 

The miscarriage took six hours and, after what I thought was the worst of it, I lay in bed with a heating pad and cried.

I thought it was time to recover and heal.

Three Days Later, the Pain Intensified

I returned to work three days after I took the medication. By that time, I was ready for a distraction from my miscarriage experience.

Sitting at home was lonely and filled with reminders that I was no longer pregnant. I didn’t want to be there anymore.

The day that I went back to work was a Wednesday, which is also the one day of the week that was the busiest in our office so there was more work and running around for me to do than usual.

Around mid-afternoon, I noticed that my cramping was intensifying and the bleeding was getting heavier.

Assuming I had just overworked my body, I excused myself to go home early to take a hot shower and lie in bed with a heating pad.

After Kerry and I ate dinner, the pain had become so intense that I felt like something had to be wrong.

My first miscarriage happened in a few hours. In the days that followed, I was sore, but my bleeding hadn’t picked back up like it was this time.

Once I noticed that I was having to change my maxi-pad every 30-45 minutes and that I was now passing blood clots, I told my husband that we should go to the emergency room.

Something just didn’t feel right.

(Editorial note: When having a miscarriage, the general rule of thumb is to go to the ER if you are soaking through a heavy maxi pad per hour, or more.)

Misoprostol Side Effects Landed Me In The Emergency Room

I will never forget the moment that everything seemed to take a turn.

If I’m being honest, this moment alone left me with post-traumatic stress disorder (PTSD) that I struggle with to this day.

The physical feeling of passing tissue and bleeding through layers of clothes is something I wish I could erase from my memory, but it’s stuck with me.

Once we arrived at the ER, I got out of the car to go through the double doors where I would check-in and start the triage process.

I felt the most intense pressure, and I could tell that I had just passed something that was very large in size.

Next, I felt something wet run down my legs.

I was wearing an adult diaper, a maxi pad, men’s briefs (trust me, after a loss, they are so comfortable), AND sweatpants. I could feel the wetness through ALL of these layers.

It had soaked through all of those layers and blood was now running down my leg.

After we checked-in, I ran to the bathroom and started to sob.

I had passed tissue that was larger than anything I had seen in my experience with miscarriage and there was blood all over me. What was happening?

Click here to subscribe

I Was Overwhelmed by My Experience with Cytotec for Miscarriage

It didn’t even occur to me that this could be part of the miscarriage because I thought that the physical aspect of our loss happened three days prior.

Over the next sevenish hours, I sat in a hospital bed in the ER and bled. A lot.

The nurses and doctors were all very nice, but it seemed that no one understood what miscarriage was like.

They kept asking me how far along I was, and I explained to them that I was 7 weeks but had recently been diagnosed with a blighted ovum.

I could tell that when they heard “7 weeks pregnant,” they assumed that the bleeding couldn’t have been very much, but they were wrong.

I kept explaining that the blood clots were the size of lemons or larger, that the blood was soaking the very small and thin pads that they kept giving me. I even had to argue with a nurse to get something other than Tylenol to help with the pain.

(Editorial note: knowing how to advocate for yourself as a patient is essential during miscarriage. Learn more about patient empowerment.)

I was in a hospital filled with people who save lives, but I felt like I was the only one caring for my situation.

After we had been sitting at the hospital for five or six hours, the OB resident came to see me and said that, because of my blood loss, he recommended I have a D&C.

I agreed and just wanted this to finally be over. I was tired, sore, in pain, and I felt dirty from all the blood that was on my legs, lady parts, shoes, etc. Please, do whatever you need to do to end this, I thought.

We Finally Returned Home, but the Questions were Just Beginning

Kerry drove me home a few hours later. I hoped that this was FINALLY the time that I could rest.

Emotionally, mentally, and physically, this miscarriage took everything out of me, and even though it seemingly was over now, I felt confused about what had just occurred.

Why did my miscarriage start and stop over the course of a few days?

Did I do something wrong by taking misoprostol for miscarriage?

Was this experience normal?

My doctor didn’t require an immediate follow-up and had a full schedule until about a month after the loss, so it would be weeks before I had some answers.

Mine Was Not an Uncommon Misoprostol Experience

A month after the traumatic night in the ER, I had an appointment with my doctor, who was our fertility specialist.

Because we had struggled with infertility prior to our first pregnancy and now suffered two miscarriages, he was our main point of contact.

When I told him about my hospital visit and experience, he wasn’t surprised.

Apparently something like 60% of women who take misoprostol has to have a D&C and/or have complications like hemorrhaging days after what they think was the miscarriage.

(Editorial note: Undefining Motherhood has not been able to find the research to support this claim, but Katy’s OR nurse told her the same thing when she went in for her D&C.)

Why did no one explain this to me? I thought.

I would have never taken the medication had I known that this was a huge risk.

In my head, taking the misoprostol gave me control, and that’s why I had chosen to take that route. But in reality, it threw me into an extremely uncontrollable situation.

We Need To Talk About the Ugly Parts of Misoprostol for Miscarriage

I quickly learned that no one tells you the ugly parts of miscarriage because they think you are fragile. (And they aren’t wrong).

However, your doctor has an ethical responsibility to warn you if something like this can happen.

No one told me what to expect when you miscarry before my first miscarriage, and I assumed that because I made it through that, I could get through anything.

Looking back, I wish I had asked more questions and had taken more time to think over my options instead of acting quickly. I wish I had read more misoprostol stories.

I was simply trying to choose the option that I thought would make this miscarriage end the quickest.

My doctor should have advised me about the potential misoprostol side effects in order for me to have made a more fully informed decision.

And that decision would have been NOT taking misoprostol for miscarriage.

What I Wish I Had Asked My Doctor About Misoprostol

If you’re ever in this situation, I hope you’ll find these questions helpful as you navigate this decision. Don’t be afraid to ask your healthcare providers questions.

Don’t be afraid to advocate for yourself.

  • What is the success rate of only having to take one dosage of Misoprostol?
  • Out of every 5 miscarriages that you diagnose, how many women choose the medicated route? And how many of those women have success?
  • How does inducing the miscarriage with Misoprostol differ from letting it happen naturally? Which is a safer option? (The answer probably depends on your gestational age, as well as how long it takes for you to miscarry without intervention.)
  • Can I start with a lower dose of Misoprostol in case my body has a reaction to the typical dose?
  • What are concerning misoprostol side effects that I should look out for? At what point should I begin to worry about said side effects?

My Advice For Choosing The Best Option For Your Miscarriage

Since I’ve now gone through two miscarriages (although one of the miscarriages was more like two in one), I’m familiar with all of the options because I’ve experienced them all.

I often wish I could go back in time and give myself some advice instead of acting quickly and trying to take the route that I thought was the quickest. 

Here are some tips for choosing your options on proceeding with the physical miscarriage:

1. Sleep on it

Yes, I know that this is a typical thing that people tell you to do when you are faced with a difficult decision, but it’s underrated. I took only a few minutes to decide what to do, and I wish I have talked more about my options with the doctor that day and taken at least 24 hours to think it over. 

When you are told that you’ve miscarried and have to plan to do so physically, your mind can’t focus on the information in front of you. 

All you hear is, “Your baby isn’t alive” and you can’t think about anything else. 

Take the rest of the day, sleep on it, and call your doctor’s office the next day with your decision. Don’t act on fear or impulse.

2. Ask questions

Don’t be afraid to ask questions or to call your office back with questions the next day. 

This is your body, your child, your fertility, and you have every right to ask any question that pops into your head.

3. Find support (including through online communities)

Something I did with my first miscarriage, but not with my second, was asking about others’ experiences with miscarriage.

I was a part of a Facebook fertility support group at the time, and I found a lot of comfort in hearing others’ stories about their losses.

People still held back on the details, but it was oddly comforting (and terribly heartbreaking) to hear their stories and see that I wasn’t alone.

Also, think about what it might’ve saved me had I heard more people’s scary misoprostol experiences. Because it turns out there are a lot. 

4. Talk with your partner

Although, as women, it’s our body that goes through the physical miscarriage, our partners should have a say and can actually offer helpful advice, too. 

After you learn about your options from your doctor and decide to take the day to think it over, talk with your partner and make sure that you are both on the same page.

5. Think through the finances

It goes without saying, but make sure that you can afford whatever option you choose. 

In our case, we have a high deductible insurance plan so paying for a D&C would have cost us thousands out of pocket.

That said, it turns out an emergency room visit cost double what the D&C alone would have cost.

Know your medical benefits and coverage and make a decision that works for your family and finances.

Miscarriage is hard enough. Don’t let it take away your financial freedom, too.

Click here to subscribe

Misoprostol Stories Can Be Different

Any time I share my Misoprostol story, I like to remind others of one thing:  just because my misoprostol experience was negative doesn’t mean that all experiences will be like mine.

I’ve met women through the online miscarriage community who had a “normal” experiences taking Misoprostol for miscarriage. Many women have no issues and are happy not to have paid for a D&C.

Alternatively, some women have reached out to me and shared that they had to take 2-3 doses and ended up having a D&C.

The truth is, anything with healthcare (and fertility) depends on the person and their situation.

But I share my misoprostol experience with you so you know the possibilities. Because had I known the high percentage of women who had negative experiences, I don’t believe I would have opted to take the Misoprostol.

If you’ve experienced what I have and felt let down by your body, your doctors, the healthcare system – just know that you aren’t alone. I see you, hear you and feel for you in every way.

What was your Misoprostol experience like? Tell us about it in the comments.

Arden posing during a maternity photoshoot while she's in her third trimester with rainbow twins

General FAQ


Is misoprostol safe for miscarriage?

Generally, yes. It’s considered safe to induce miscarriage and is often used to induce the miscarriage in the privacy of a patient’s home without a healthcare professional. Personally, I think that it should only be used in a medical setting such as a hospital or doctor’s office. I wouldn’t recommend a friend choose this option, especially at home alone.


What to expect after taking misoprostol?

Many doctors will tell you to expect a heavy period after you take the misoprostol. But like any miscarriage, a “heavy period” is usually a major understatement. Physically, you can expect cramping, bleeding, blood clots, intense pressure in your vagina, pain, and potentially vomiting from the pain.


How long does misoprostol stay in the body?

The half-life of misoprostol is only 20-40 minutes. But, as with any medication, traces can remain in your system for a long time.


How long does it take for misoprostol to dissolve?

There are a few different forms of Misoprostol. One dissolves under your tongue or can be placed near your cervix and left to dissolve or you can take the medication by mouth. Placing the tablet near your cervix helps the medication act faster, but many doctors recommend taking it by mouth.

Sharing is caring!